Author

Zhen Chen

Shanghai Medical College of Fudan UniversityORCID 0000-0002-4502-0801Unclaimed ORCID profile · follow to get notified of new preprints

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Zhen Chen2 papers · Beijing University of Technology

Biology Disciplines

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Cancer Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Feifei Zhang· 1 shared Hongwu Yu· 1 shared Huiyi HeiD· 1 shared Jing Xie· 1 shared Jingjing Zhao· 1 shared Kunyu Liu· 1 shared Nan QiniD· 1 shared Peng LiniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Feifei Zhang

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2 papers

Recent·Most cited

Harnessing Tumor-Specific Transcript Diversity Uncovers a Shared Neoantigen Reservoir for Pancreatic Ductal Adenocarcinoma

Jingjing Zhao, Qiaojuan Li, Peng Lin, Yu Yang, Hongwu Yu, Yifan Wen, Wenqian Yu, Huiyi He, Sichen Tao, Feifei Zhang, Yan Li, Zhixiang Hu, Jing Xie, Zhen Chen, Shenglin Huang

This paper introduces NeoAPP, a tool to identify tumor-specific transcript-derived neoantigens in PDAC, revealing a large neoantigen reservoir that could improve immunotherapy.

MedComm · Jul 30, 2026Peer-reviewedCancer Biology

Transcriptome and metabolome analyses reveal novel genetic targets for L-tryptophan overproduction in Corynebacterium glutamicum

Yufei Dong, Rongsheng Gao, Nan Qin, Kunyu Liu, Youmeng Liu, Zhen Chen

The paper identifies two genetic targets, glnK and sugR, that enhance L-tryptophan production in Corynebacterium glutamicum through transcriptome and metabolome analyses.

bioRxiv · May 7, 2025 · PreprintSynthetic Biology