Reexamination of N-terminal domains of Syntaxin-1 in vesicle fusion from central murine synapses
Gülçin Vardar, Andrea Salazar-Lázaro, Marisa M. Brockmann, Marion Weber‐Boyvat, Sina Zobel, Victor Wumbor-Apin Kumbol, Thorsten Trimbuch, Christian Rosenmund
This study reexamines the roles of Syntaxin-1's N-peptide and Habc-domain in synaptic vesicle fusion using a mouse model, showing the Habc-domain is essential while the N-peptide has regulatory functions.
eLife · Aug 24, 2021Peer-reviewedNeuroscience