Neurotransmitter release is triggered by a calcium-induced rearrangement in the Synaptotagmin-1/SNARE complex primary interface
Estelle Toulmé, Andrea Salazar-Lázaro, Thorsten Trimbuch…·Christian Rosenmund
This study identifies two distinct regions in the synaptotagmin-1/SNARE complex interface that mediate different functions in neurotransmitter release and shows that Ca2+ triggers a rearrangement of this interface.