Victor Wumbor-Apin Kumbol

This study shows that murine TLR8 is a functional nucleic acid sensor, responding to synthetic and endogenous ligands and restoring TLR7-dependent transcriptional programs in vivo.

This study reexamines the roles of Syntaxin-1's N-peptide and Habc-domain in synaptic vesicle fusion using a mouse model, showing the Habc-domain is essential while the N-peptide has regulatory functions.