Author

David Friedecký

University Hospital OlomoucORCID 0000-0002-3448-9073Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1 Organism:rat· 1

Frequent Co-Authors

Aleš KvasničkaiD· 2 shared Dana DobešováiD· 2 shared Radana BrumarováiD· 2 shared Alena MichalicováiD· 1 shared Anastasiia NovakiD· 1 shared Andrej KováčiD· 1 shared Anna Maria GórskaiD· 1 shared Carla Horváth· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Aleš KvasničkaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

GPR180 deficiency impairs mitochondrial function and insulin secretion in pancreatic β-cells

Matus Antal, Tina Dahlby, Peter Makovicky, Anastasiia Novak, Carla Horváth, Daniela Staníková, Simona Gazova, Radana Brumarová, Eliška Ivanovová, Martina Horejšová, David Friedecký, Oľga Križanová, Marta Novotová, Daniela Gašperíková, Christian Wolfrum, , Lucia Balážová

This study shows that GPR180 deficiency impairs mitochondrial function and first-phase insulin secretion in pancreatic β-cells without affecting insulin sensitivity.

Molecular Metabolism · Jul 16, 2026Peer-reviewedPhysiology

ABCA7 deficiency exacerbates glutamate excitotoxicity in Alzheimer's disease mice -- a new pharmacological target for Glu-related neurotoxicity

Anna Maria Górska, Irene Santos‐García, Aleš Kvasnička, Dana Dobešová, David Friedecký, Jacob Gildenblat, Jens Pahnke

This paper investigates how ABCA7 deficiency worsens glutamate excitotoxicity in Alzheimer's disease mice, identifying ABCA7 as a potential pharmacological target for Glu-related neurotoxicity.

Progress in Neurobiology · Feb 5, 2026Peer-reviewedNeuroscience

Changes in lipid metabolism track with the progression of neurofibrillary pathology in tauopathies.

Dominika Olešová, Dana Dobešová, Petra Majerová, Radana Brumarová, Aleš Kvasnička, Štěpán Kouřil, Eva Stevens, Jozef Hanes, Ľubica Fialová, Alena Michalicová, Juraj Piešťanský, Jakub Šinský, Petr Kaňovský, David Friedecký, Andrej Kováč

The paper shows that lipid metabolism changes with tauopathy progression, linking pathological tau to altered lipid production and microglial lipid droplet accumulation.

Journal of Neuroinflammation · Mar 27, 2024Peer-reviewedNeuroscience