Author

Aleš Kvasnička

University Hospital OlomoucORCID 0000-0001-5973-316XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Assay:metabolomics· 2 Organism:mouse· 2 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Dana DobešováiD· 2 shared David FriedeckýiD· 2 shared Alena MichalicováiD· 1 shared Andrej KováčiD· 1 shared Anna Maria GórskaiD· 1 shared Bujinlkham Buyantogtokh· 1 shared Dominika OlešováiD· 1 shared Eva Stevens· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersNeuroscience

Dana DobešováORCID

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3 papers

Recent·Most cited

NeuroscienceProgress in NeurobiologyPeer-reviewedFeb 5, 2026

ABCA7 deficiency exacerbates glutamate excitotoxicity in Alzheimer's disease mice -- a new pharmacological target for Glu-related neurotoxicity

Anna Maria Górska, Irene Santos‐García, Aleš Kvasnička…·Jens Pahnke

This paper investigates how ABCA7 deficiency worsens glutamate excitotoxicity in Alzheimer's disease mice, identifying ABCA7 as a potential pharmacological target for Glu-related neurotoxicity.

4 citationstop 1%

mousestatistical model

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BioinformaticsNature CommunicationsPeer-reviewedNov 28, 2024

MS-DIAL 5 multimodal mass spectrometry data mining unveils lipidome complexities

Hiroaki Takeda, Yuki Matsuzawa, Manami Takeuchi…·Hiroshi Tsugawa

The paper introduces MS-DIAL 5, a tool for analyzing multimodal mass spectrometry data to elucidate lipid structures and localization using structural annotations.

140 citationstop 1%

humanmouse

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NeuroscienceJournal of NeuroinflammationPeer-reviewedMar 27, 2024

Changes in lipid metabolism track with the progression of neurofibrillary pathology in tauopathies.

Dominika Olešová, Dana Dobešová, Petra Majerová…·Andrej Kováč

The paper shows that lipid metabolism changes with tauopathy progression, linking pathological tau to altered lipid production and microglial lipid droplet accumulation.

30 citationstop 2%

ratmetabolomics

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