Scott J. Emrich

TRPML1 signaling at lysosomes-mitochondria nexus drives triple-negative breast cancer mitophagy, metabolic reprogramming and chemoresistance

This study identifies TRPML1 as a key regulator of mitochondrial function and chemoresistance in TNBC by modulating lysosomal-mitochondria signaling and autophagy.

IRF7 controls spontaneous autoimmune germinal center and plasma cell checkpoints

This study identifies B cell-intrinsic and -extrinsic mechanisms by which IRF7 promotes spontaneous autoimmune germinal center and plasma cell responses, autoantibody production, and SLE development.

Evolutionary superscaffolding and chromosome anchoring to improve Anopheles genome assemblies

The paper improves Anopheles genome assemblies using comparative genomics methods and experimental data, resulting in more contiguous and chromosomally anchored assemblies.

Minimum Information for Reusable Arthropod Abundance Data (MIReAAD)

The paper introduces MIReAAD, a framework for standardizing arthropod abundance data to improve reusability and comparability across studies.