Cancer BiologyCell ReportsPeer-reviewed
P-cadherin mechanoactivates tumor- mesothelium metabolic coupling to promote ovarian cancer metastasis
Jing Ma, Sally Kit Yan To, Katie Sze Wai Fung…·Alice S.T. Wong
This study shows that P-cadherin-mediated mechanical forces on mesothelial cells enhance lipid production in ovarian cancer cells, promoting metastasis through lactate-driven lipogenesis.
13 citations