Extracellular Nanobody Screening using Conformationally Stable GPCR
Xin Zhang, Kaixuan Gao, Jia Nie, Hengyu Meng, Xiaoou Sun, Jiawei Zhao, Xiangyu Liu
The paper stabilizes GPCRs in specific conformations using a fusion protein and screens nanobodies to identify conformation-specific binders.
bioRxiv · Mar 25, 2025 · PreprintBiochemistry