Author

Phoebe C. R. Parrish

University of WashingtonORCID 0000-0002-3530-0105Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:whole-genome sequencing· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alice H. BergeriD· 2 shared Amira Ellison· 1 shared Amy E. RobertsiD· 1 shared Austin M. GabeliD· 1 shared Barbara R. PoberiD· 1 shared Beth A. KozeliD· 1 shared Beth MartiniD· 1 shared C.A. Morris· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersGenomics

Alice H. BergerORCID

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Author profile →

3 papers

Recent·Most cited

A multiplex, prime editing framework for identifying drug resistance variants at scale

Florence M. Chardon, Chase C. Suiter, Riza M. Daza, Nahum T. Smith, Phoebe C. R. Parrish, Troy A. McDiarmid, Jean‐Benoît Lalanne, Beth Martin, Diego Calderon, Amira Ellison, Alice H. Berger, Jay Shendure, Lea M. Starita

This paper introduces prime-SGE, a prime editing framework for assessing drug resistance variants across multiple oncogenes in a single experiment.

bioRxiv · Jul 27, 2023 · PreprintGenomics

Pathway analysis identifies novel non-synonymous variants contributing to extreme vascular outcomes in Williams-Beuren syndrome

D. Liu, Charles John Billington, N. Raja, Zoë C. Wong, Mark David Levin, Wolfgang Resch, Camille Alba, Daniel N. Hupalo, Elisa Biamino, Maria Francesca Bedeschi, Maria Cristina Digilio, Gabriella Maria Squeo, R. Villa, Phoebe C. R. Parrish, Russell H. Knutsen, , Beth A. Kozel

The paper identifies novel non-synonymous variants associated with extreme vascular outcomes in Williams-Beuren syndrome through whole-genome sequencing and pathway analysis.

medRxiv · Sep 21, 2022 · PreprintGenetic & Genomic Medicine

Discovery of synthetic lethal and tumor suppressive paralog pairs in the human genome

Phoebe C. R. Parrish, James D. Thomas, Austin M. Gabel, Shriya Kamlapurkar, Robert K. Bradley, Alice H. Berger

The paper identifies synthetic lethal and tumor suppressive paralog pairs in the human genome using a CRISPR-based approach, revealing new drug targets and essential gene families.

Cell Reports · Aug 1, 2021Peer-reviewedGenomics