Author

Françoise Bleicher

École Normale Supérieure de LyonORCID 0000-0002-3534-8985Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:protein structure· 2 Assay:DNA methylation· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein design· 1

Frequent Co-Authors

Samir MerabetiD· 3 shared Benjamin GilletiD· 2 shared Cindy KundlacziD· 2 shared Nawal Hajj SleimaniD· 2 shared Sandrine HughesiD· 2 shared Agnès DumontiD· 1 shared Arnaud GautieriD· 1 shared Christelle ForcetiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersMolecular Biology

Samir MerabetORCID

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3 papers

Recent·Most cited

Characterizing drug activity with sensitive interactomes in human living cells

Cindy Kundlacz, Nawal Hajj Sleiman, Frédéric Marmigère, Benjamin Gillet, Sandrine Hughes, Laurent Gilquin, Hélène Duplus‐Bottin, Agnès Dumont, Gaël Yvert, Françoise Bleicher, Arnaud Gautier, Isabelle Coste, Toufic Renno, Samir Merabet

The paper introduces a method to identify drug-sensitive protein-protein interactions in live cells using ERK1 as a case study, showing how inhibitory molecules affect these interactions.

bioRxiv · Nov 20, 2025 · PreprintMolecular Biology

A micro-evolutionary change in target binding sites as key determinant of Ultrabithorax function in Drosophila.

Soumen Khan, Saurabh J. Pradhan, Guillaume Giraud, Françoise Bleicher, Rachel Paul, Samir Merabet, Lingadahalli Subrahmanya Shashidhara

The paper identifies a micro-evolutionary change in Ubx binding sites as a determinant of differential Ubx function between Drosophila and Apis mellifera.

Journal of Molecular Evolution · Jun 21, 2023Peer-reviewedDevelopmental Biology

A live cell protein complementation assay for ORFeome-wide probing of human HOX interactomes

Yunlong Y. Jia, Jonathan Reboulet, Benjamin Gillet, Sandrine Hughes, Christelle Forcet, Violaine Tribollet, Nawal Hajj Sleiman, Cindy Kundlacz, Jean-Marc Vanacker, Françoise Bleicher, Samir Merabet

The paper introduces Cell-PCA, a live cell protein complementation assay, to probe human HOX interactomes, revealing novel cofactors and molecular properties.

Cells · Jan 3, 2023Peer-reviewedMolecular Biology