Author

Samit Ghosh

University of PittsburghORCID 0000-0002-3536-3077Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Domenic FilingeriiD· 1 shared Enrico Maria NovelliiD· 1 shared Hong WangiD· 1 shared Jeongkyung LeeiD· 1 shared Joey Danvers· 1 shared Kumar AriD· 1 shared Lesley M. FoleyiD· 1 shared Mousumi MoulikiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperPathology

Domenic FilingeriORCID

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2 papers

Recent·Most cited

Hepatocyte TEAD1 drives epithelial-stromal remodeling during cholestatic liver injury

Kumar Ar, Jeongkyung Lee, Vinny Negi, Varun Mandi, Domenic Filingeri, Joey Danvers, Rajat Pant, Samit Ghosh, Mousumi Moulik, Vijay K. Yechoor

This study shows hepatocyte TEAD1 promotes fibrosis and inflammation in cholestatic liver injury but not bile acid metabolism, suggesting it as a therapeutic target in PSC.

bioRxiv · May 26, 2026 · PreprintPathology

Frataxin deficiency in the astrocytes drives neurocognitive impairment in sickle cell disease mice

Enrico Maria Novelli, Shane C Lenhart, Lesley M. Foley, Nandinii Sekar, Paritosh Mondal, Hong Wang, T. Kevin Hitchens, Samit Ghosh, Stephen Y. Chan, Xiaoming Hu, Rimi Hazra

This study shows that frataxin deficiency in astrocytes worsens cognitive impairment in sickle cell disease mice, suggesting FXN as a potential therapeutic target.

bioRxiv · Dec 20, 2024 · PreprintNeuroscience