Author

Bo Tao

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Genomics· 1 Pathology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Assay:spatial transcriptomics· 5 Research Focus:cell type annotation· 4 Approach:deep learning· 4 Approach:experimental assay· 4 Research Focus:differential expression· 3 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2

Frequent Co-Authors

Rong FaniD· 5 shared Archibald EnninfuliD· 3 shared Haikuo LiiD· 3 shared Sidi CheniD· 3 shared Xiaolong TianiD· 3 shared Zhiliang BaiiD· 3 shared Alev BaysoyiD· 2 shared Anthony A. FungiD· 2 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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5 shared papersImmunology

Rong FanORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Spatial Glyco-Codes Define Human Liver Pathology and Progression

Xiaolong Tian, Anthony A. Fung, Xingbo Shang, Dingyao Zhang, Binfan Chen, Lei Zhang, K E X I N Li, Mei Zhong, Yifan Deng, Mingyu Yang, Yao Lu, Bo Tao, Fu Gao, Alev Baysoy, Xiao Louise Lin, , Rong Fan

This study introduces spatial-GPT, a platform for spatial glycan, protein, and transcriptome profiling in human liver tissues, revealing glyco-codes that define disease states and progression.

bioRxiv · Jul 12, 2026 · PreprintPathology

Human Lymph Node Cellular Senescence Atlas Reveals Age-Dependent Alteration in Germinal Center B Cell Function and Niches

Negin Farzad, Archibald Enninful, Yao Lu, Fabio Parisi, Anthony A. Fung, Yumi Kwon, Yajuan Li, Margaux Labrosse, Mingyu Yang, Francesco Strino, Liang Chen, Junchen Yang, Mei Zhong, Fu Gao, Bo Tao, , Rong Fan

This study maps age-related cellular senescence in human lymph nodes, identifying senescence markers and spatial shifts in germinal center B cells.

bioRxiv · Apr 6, 2026 · PreprintImmunology

CAR-T-drug conjugate against solid tumor

Shan Xin, Yanzhi Feng, Feifei Zhang, Jiang Yu, Chuanpeng Dong, Bo Tao, Kaiyuan Tang, Qihao Wu, Binfan Chen, Ping Ren, Nipun Verma, Chuan Liu, Kazushi Suzuki, Xinyu Ling, Daniel Park, , Sidi Chen

This paper introduces CAR-T-drug conjugates (CAR-T-D-C) to improve CAR-T therapy for solid tumors by combining chemotherapy with CAR-T cells, enhancing tumor infiltration and immune response.

bioRxiv · Jan 2, 2026 · PreprintImmunology

Spatially Resolved in vivo CRISPR Screen Sequencing via Perturb-DBiT

Alev Baysoy, Xiaolong Tian, Feifei Zhang, Paul A. Renauer, Zhiliang Bai, Hao Shi, Haikuo Li, Bo Tao, Mingyu Yang, Archibald Enninful, Fu Qiang Gao, Guangchuan Wang, Wanqiu Zhang, Thao Tran, Nathan Heath Patterson, , Rong Fan

Perturb-DBiT co-sequences spatial transcriptomes and gRNAs on one tissue section, supporting genome-wide in vivo CRISPR screens in FFPE and fresh-frozen tumors across three cancer models.

bioRxiv · Nov 18, 2024 · PreprintGenomics✦ In-depth digest

Spatially Exploring RNA Biology in Archival Formalin-Fixed Paraffin-Embedded Tissues

Zhiliang Bai, Dingyao Zhang, Yan Ping Gao, Bo Tao, Daiwei Zhang, Shuozhen Bao, Archibald Enninful, Yadong Wang, Haikuo Li, Graham Su, Xiaolong Tian, Ningning Zhang, Yang Xiao, Yang Liu, Mark Gerstein, , Rong Fan

This paper introduces Patho-DBiT, a method for spatial transcriptomics in FFPE tissues, enabling RNA biology analysis including splicing, variants, and regulatory networks in clinical samples.

Cell · Sep 30, 2024Peer-reviewedSystems Biology