Bruno Monier

Cell exit during EMT is mechanically triggered independently of E-Cadherin loss

The paper shows that cell exit during EMT in Drosophila is mechanically driven by apical detachment requiring Spectrin, independent of E-Cadherin loss.

Mechanical state of pre-tumoral epithelia dictates subsequent tumour aggressiveness

The paper shows that increased cell contractility in pre-tumoral tissues drives tumour aggressiveness through dysplasia and junction weakening.

Mechanical control of morphogenetic robustness in an inherently challenging environment

The paper shows that junctional Myosin II planar polarity ensures stereotyped morphogenesis by channeling forces and isolating fold domains from mechanical noise.