Magali Suzanne

This paper introduces a method for absolute force measurements in living tissues with sub-piconewton precision, validated in Drosophila pupae and embryos.

The paper investigates how nuclei respond to mechanical forces during EMT using Drosophila mesoderm invagination, showing spatially distinct transcriptional responses.

The paper shows that cell exit during EMT in Drosophila is mechanically driven by apical detachment requiring Spectrin, independent of E-Cadherin loss.

The paper shows that increased cell contractility in pre-tumoral tissues drives tumour aggressiveness through dysplasia and junction weakening.

The paper shows that compressive stress during Drosophila leg development drives apoptosis through lateral tension and Piezo1, contributing to tissue folding.

The paper introduces mBeRFP, a red fluorescent protein that enables multichannel live imaging with minimal crosstalk and low photobleaching, suitable for applications like FRAP and laser ablation in Drosophila.

The paper shows that junctional Myosin II planar polarity ensures stereotyped morphogenesis by channeling forces and isolating fold domains from mechanical noise.