Sophie Theis

The paper shows that boundary constraints influence the spatial patterning of cell fates during development through a reaction-diffusion model and Wnt signaling.

The paper quantitatively evaluates nine green and eight red fluorophores in Drosophila embryos to identify optimal choices based on bleaching, folding, and imaging conditions.

This study investigates how the zebrafish myotome forms a robust 3D structure through a structural transition involving cell rearrangement and mechanical plasticity.

This paper develops a continuum framework to study stress anisotropy in 3D curved biological layers, showing how curvature and cell mechanics lead to irregular cellular shapes like scutoids.

CellMet extracts 3D shape metrics from cell and tissue segmentations to improve analysis of cell organization in densely packed tissues.

The paper shows that junctional Myosin II planar polarity ensures stereotyped morphogenesis by channeling forces and isolating fold domains from mechanical noise.