Author

Zhiyun Wei

Tongji UniversityORCID 0000-0002-3554-4142Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Anna M. KrichevskyiD· 3 shared Rosalia RabinovskyiD· 3 shared Rachid El FatimyiD· 2 shared Abdallah ElkhaliD· 1 shared Adam Cantlon· 1 shared Christina Muratore· 1 shared Colin Hortman· 1 shared Darrick T. BaluiD· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersNeuroscience

Anna M. KrichevskyORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Small Molecule Inducers of Neuroprotective miR-132 Identified by HTS-HTS in Human iPSC-derived Neurons

Lien D. Nguyen, Zhiyun Wei, M. Catarina Silva, Sergio Barberán-Soler, Rosalia Rabinovsky, Christina Muratore, Jonathan M. S. Stricker, Colin Hortman, Tracy L. Young‐Pearse, Stephen J. Haggarty, Anna M. Krichevsky

The paper identifies small molecule inducers of miR-132 in human iPSC-derived neurons using HTS-HTS, showing neuroprotective effects against neurodegenerative phenotypes.

bioRxiv · Nov 1, 2022 · PreprintNeuroscience

A nuclear function for an oncogenic microRNA as a modulator of snRNA and splicing

Rachid El Fatimy, Yanhong Zhang, Evgeny Deforzh, Mahalakshmi Ramadas, Harini Saravanan, Zhiyun Wei, Rosalia Rabinovsky, Nadiya M. Teplyuk, Erik J. Uhlmann, Anna M. Krichevsky

The paper shows miR-10b interacts with U6 snRNA, altering splicing and affecting cell viability through changes in CDC42 isoforms and levels.

Molecular Cancer · Jan 15, 2022Peer-reviewedMolecular Biology

MicroRNA-132 provides neuroprotection for tauopathies via multiple signaling pathways

Rachid El Fatimy, Shaomin Li, Zhicheng Chen, Tasnim Mushannen, Sree Gongala, Zhiyun Wei, Darrick T. Balu, Rosalia Rabinovsky, Adam Cantlon, Abdallah Elkhal, Dennis J. Selkoe, Kai‐Christian Sonntag, Dominic M. Walsh, Anna M. Krichevsky

This study shows miR-132 protects neurons from tauopathy-related damage by regulating multiple pathways and reducing Tau pathology in mice.

Acta Neuropathologica · Jul 7, 2018Peer-reviewedNeuroscience