Yanhong Zhang

The paper introduces SCIENCE-seq, a single-cell interactomics platform that maps RNA-RNA and DNA-DNA interactions in cancer, identifying therapeutic targets through chromatin architectures.

This study identifies tRNA-derived fragments (tRFs) as key regulators of Tau aggregation in Alzheimer's disease and shows their potential as therapeutic targets.

The paper shows miR-10b interacts with U6 snRNA, altering splicing and affecting cell viability through changes in CDC42 isoforms and levels.

This study identifies PARP1 as a key driver of oligodendrocyte differentiation and myelination, showing its role in both developmental and remyelination processes in the CNS.