Katharina Scheibner

This study improves the safety of stem cell-derived islets by enriching endocrine cells and reducing off-target cell types, enhancing long-term in vivo outcomes.

This study identifies Synaptotagmin 13 as a key regulator of endocrine cell egression and islet formation through its role in cell polarity and basement membrane remodeling.

This study shows that Foxa2 binding site selection is influenced by chromatin environment and that chromatin opening requires collaboration with other transcription factors during endoderm differentiation.