Alcohol reverses the effects of KCNJ6 (GIRK2) noncoding variants on excitability of human glutamatergic neurons
Dina Popova, Isabel Gameiro‐Ros, Mark M. Youssef, Petronio D. Zalamea, Ayeshia Morris, Iya Prytkova, Azadeh Jadali, Kelvin Y. Kwan, Chella Kamarajan, Jessica E. Salvatore, Xiaoling Xuei, David Balin Chorlian, Bernice Porjesz A, Samuel Kuperman C, Danielle M. Dick, , Ronald P. Hart
This study shows that KCNJ6 noncoding variants increase excitability in human glutamatergic neurons, an effect reversed by ethanol exposure.
Molecular Psychiatry · Oct 7, 2022Peer-reviewedNeuroscience