Iya Prytkova

This study investigates the phenotypic complexities of rare heterozygous NRXN1 deletions, showing cell-type-specific synaptic effects through LOF and GOF mechanisms, highlighting the need for precision medicine strategies.

This paper develops a high-throughput method to measure neuronal activity in human iPSC-derived glutamatergic neurons using Mg2+-free ACSF and confirms donor-specific firing patterns.

The paper investigates how upregulated GIRK2 affects ethanol-induced changes in human neurons, showing it counteracts excitability and respiration changes.

This study shows that KCNJ6 noncoding variants increase excitability in human glutamatergic neurons, an effect reversed by ethanol exposure.

This study develops a method to efficiently generate dopaminergic neurons from hiPSCs and shows they model psychiatric disease risk genes.