Reversible and Causal Epigenetic Information Loss in Liver Aging and Disease
Roni B Shtark, Naor Sagy, Noga Korenfeld, Maayan Gal, Ido Goldstein, Daniel Zvi Bar
This paper shows that liver-specific methylation sites regress toward a pan-tissue average during aging and disease, and this loss can be partially reversed by fasting.
PNAS Nexus · Apr 1, 2026Peer-reviewedMolecular Biology