Ido Goldstein

This paper shows that liver-specific methylation sites regress toward a pan-tissue average during aging and disease, and this loss can be partially reversed by fasting.

This study shows that JAK1/2 inhibition with ruxolitinib improves survival and body weight in lung cancer models by increasing food intake and restoring metabolic function.

This study shows bile acids bind to an exposed cavity on the glucocorticoid receptor, affecting its self-assembly and transcriptional activity.

The paper shows that repeated fasting events sensitize enhancers and gene expression to enhance ketogenesis in mice.

The paper identifies transcriptional cascades during fasting that amplify gluconeogenesis and trigger a secondary wave of ketogenic gene transcription through hormone-induced transcription factors.