Author

Vahitha B. Abdul‐Salam

Queen Mary University of LondonORCID 0000-0002-3568-9771Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:protein structure· 2 Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Angela Serrano-Sanchez· 2 shared Encarnación Medina‐CarmonaiD· 2 shared Felipe OssaiD· 2 shared Jose‐Luis Ortega RoldaniD· 2 shared Abdelaziz El‐HamdaouiiD· 1 shared Fisayo Andrew OlotuiD· 1 shared Gary S. ThompsoniD· 1 shared Jack Bragg· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

Angela Serrano-Sanchez

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2 papers

Recent·Most cited

Mechanistic Elucidation of CLIC1 Membrane Insertion via Structural and Dynamic Modulation

Joseph Cassar, Angela Serrano-Sanchez, Jack Bragg, Encarnación Medina‐Carmona, Felipe Ossa, Gary S. Thompson, Vahitha B. Abdul‐Salam, Lorena Varela, Jose‐Luis Ortega Roldan

This study elucidates the mechanism of CLIC1 membrane insertion through structural and dynamic analysis, revealing Zn2+-induced conformational changes and oligomerization as critical steps.

bioRxiv · Jan 19, 2025 · PreprintBiochemistry

Structure-based discovery and in vitro validation of selective inhibitors of Chloride Intracellular Channel 4 protein.

Fisayo Andrew Olotu, Encarnación Medina‐Carmona, Angela Serrano-Sanchez, Felipe Ossa, Abdelaziz El‐Hamdaoui, Özlem Taştan Bishop, Jose‐Luis Ortega Roldan, Vahitha B. Abdul‐Salam

This study identifies and validates FDA-approved drugs as inhibitors of CLIC4 using structural bioinformatics and experimental assays.

Computational and Structural Biotechnology Journal · Dec 24, 2022Peer-reviewedMolecular Biology