Paul Andrew Rowley

The paper uses AlphaFold and molecular dynamics to model Saccharomyces killer toxins, revealing structural homology and functional insights into their mechanisms.

The paper surveys killer yeast prevalence in attine ant fungus gardens, identifies a new killer toxin Ksino, and highlights its antifungal activity and ecological significance.

The paper introduces an automated bioinformatics pipeline called HitList to identify novel antifungal targets in fungi by analyzing genomic and proteomic data, discovering eight new potential targets.

The paper defines domain boundaries of K1-like killer toxins across yeast species and identifies conserved alpha domains with cytotoxic activity.

This study shows that inactivating the upf31 gene in a plasmid improves its maintenance in E. coli by altering gene regulation, demonstrating how plasmid evolution can affect host range.

This study identifies six critical amino acids in NUP153 essential for HIV capsid interaction using computational and experimental methods.

The paper identifies and characterizes a novel totivirus, PmV-L-A, in the yeast Pichia membranifaciens, revealing structural and evolutionary relationships with other totiviruses.

This study uses high school students to experimentally evolve S. cerevisiae and identifies mutations and epistatic interactions affecting azole resistance.

The paper identifies a novel family of killer toxins in Saccharomyces yeasts, showing their acquisition via horizontal gene transfer and diversification through positive selection and gene amplification.