Mark D. Lee

Lean breast adipocytes secrete an oxylipin that suppresses breast cancer via ferroptosis

The paper identifies 9S-HODE, a lipid secreted by lean adipocytes, as a ferroptosis inducer that suppresses breast cancer while sparing normal cells, with therapeutic potential in obese mice.

A Novel Virus Discovered in the Yeast Pichia membranifaciens.

The paper identifies and characterizes a novel totivirus, PmV-L-A, in the yeast Pichia membranifaciens, revealing structural and evolutionary relationships with other totiviruses.

The Species-specific Acquisition and Diversification of a Novel Family of Killer Toxins in Budding Yeasts of the Saccharomycotina.

The paper identifies a novel family of killer toxins in Saccharomyces yeasts, showing their acquisition via horizontal gene transfer and diversification through positive selection and gene amplification.