Soluble amyloid-β precursor peptide does not regulate GABAB receptor activity
Pascal Dominic Rem, Vita Sereikaité, Diego Fernández‐Fernández, Sebastian Reinartz, Daniel Ulrich, Thorsten Fritzius, Luca Trovò, Salomé Roux, Ziyang Chen, Philippe Rondard, Jean‐Philippe Pin, Jochen Schwenk, Bernd Fakler, Martin Gassmann, Tania Rinaldi Barkat, , Bernhard Bettler
This study shows that APP17, a peptide derived from APP, does not regulate GABAB receptor activity in heterologous cells or neurons, suggesting sAPP acts through other receptors.
eLife · Jan 23, 2023Peer-reviewedNeuroscience