Macrophage PIM1 Drives Atherosclerosis by Enhancing Foam Cell Formation Via CD36
Mirza Ahmar Beg, Quoc Quang Luu, Wenjing Chen, Yaxin Wang, Gang Xin, Weiguo Cui, Roy L. Silverstein, Yiliang Chen
This study shows that PIM1 in macrophages enhances CD36 expression and function, promoting foam cell formation and atherosclerosis, and that targeting this pathway could reduce plaque progression.
Arteriosclerosis Thrombosis and Vascular Biology · Aug 6, 2026Peer-reviewedImmunology