Jong Kyoung Kim

This study shows that Pcpe2 in adipose tissue contributes to inflammation and fibrosis in obesity and that its absence reduces these effects and enhances adipocyte differentiation.

The paper identifies ETV4 as a transcription factor that restricts cytotoxic exhausted CD8+ T cell differentiation and shows CD74+ Tex cells correlate with improved survival.

This paper introduces a method to increase the proportion of correctly repaired hepatocytes in the liver through transient gene inhibition and transgene delivery, achieving a 25% increase in targeted cells and five-fold transgene expression.

The paper introduces Red2Flpe-SCON, a multicolor system for generating mosaic conditional knockout mice, and uses it to show Sox2 is not essential for stem cell maintenance but for proliferation and differentiation.

This study shows that Hippo-deficient cardiac fibroblasts differentiate into osteochondroprogenitors and interact with macrophages, promoting fibrosis through CSF1 signaling.

The paper introduces a method called soft windowing to improve analysis of high-throughput phenotyping data by reducing false positives and increasing significant results.

The paper investigates how flipping between Polycomb-repressed and active transcriptional states affects gene expression noise using integrated histone modification and single-cell RNA-seq data.