Author

Scott E. James

City Of Hope National Medical CenterORCID 0000-0002-3601-6819Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1

Frequent Co-Authors

Harold Kunal EliasiD· 2 shared Jonathan U. PelediD· 2 shared Marcel R.M. van den BrinkiD· 2 shared Teng FeiiD· 2 shared Adhithi RajagopalaniD· 1 shared Alexander P. Boardman· 1 shared Alyssa MassaiD· 1 shared Amina LazrakiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Harold Kunal EliasORCID

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2 papers

Recent·Most cited

Dietary fiber intake associates with improved survival and microbiomecomposition in allogeneic hematopoietic cell transplantation

Jenny Paredes, Tyler Funnell, Peter A. Adintori, Anqi Dai, Natalie Smith, Ruben J. Jesus Faustino Ramos, Preet Kaur, Zeyang Li, Khyati Pathak, Jennifer Funes, Kristen Victor, Romina Ghale, Nathan Doung, Jennifer M. Haber, Keimya D. Sadeghi, , Marcel R.M. van den Brink

This study shows that higher dietary fiber intake improves survival and reduces GVHD in hematopoietic cell transplant patients, with microbiome-mediated effects.

bioRxiv · Jun 4, 2026 · PreprintCancer Biology

Leucine zipper-based sorting system enables generation of multi-functional CAR T cells

Scott E. James, Sophia Chen, Brandon D. Ng, Jacob S. Fischman, Lorenz Jahn, Alexander P. Boardman, Adhithi Rajagopalan, Harold Kunal Elias, Alyssa Massa, Dylan Manuele, Katherine B. Nichols, Amina Lazrak, Nicole MynYi Lee, Teng Fei, Susan DeWolf, , Marcel R.M. van den Brink

This paper introduces a leucine zipper-based sorting system to generate T cells with multiple CARs and switch receptors, enhancing their ability to target heterogeneous tumors.

bioRxiv · Sep 13, 2023 · PreprintSynthetic Biology