Toyoshi Fujimoto

ATG deficiency impairs stationary-phase microlipophagy through acetic acid-induced clustering of Niemann-Pick type C proteins

The paper shows that ATG deficiency impairs stationary-phase microlipophagy in yeast due to acetic acid-induced NPC protein clustering, which can be rescued by reducing extracellular acetic acid.

Phase separation promotes Atg8 lipidation for autophagy progression

This study shows that phase separation of the Atg1 complex forms the PAS, which facilitates Atg8 lipidation and autophagosome formation in yeast.