Author

Hitoshi Nakatogawa

Cell Biology CenterORCID 0000-0002-5828-0741Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:yeast· 2 Approach:mechanistic / dynamical model· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Chika Kakuta· 2 shared Junko Shimasaki· 2 shared Nobuo N. NodaiD· 2 shared Tetsuya KotaniiD· 2 shared Yūko FujiokaiD· 2 shared Hiroyuki KumetaiD· 1 shared Kazuaki MatobaiD· 1 shared Kuninori SuzukiiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCell Biology

Chika Kakuta

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Phase separation promotes Atg8 lipidation for autophagy progression

Yūko Fujioka, Takuma Tsuji, Tetsuya Kotani, Hiroyuki Kumeta, Chika Kakuta, Junko Shimasaki, Toyoshi Fujimoto, Hitoshi Nakatogawa, Nobuo N. Noda

This study shows that phase separation of the Atg1 complex forms the PAS, which facilitates Atg8 lipidation and autophagosome formation in yeast.

Nature Structural & Molecular Biology · Sep 16, 2025Peer-reviewedCell Biology

Atg1 phosphorylates Atg2 to gate phospholipid flow through a continuous conduit for autophagosome biogenesis

Yuji Sakai, Tetsuya Kotani, Tatsuro Maruyama, Kazuaki Matoba, Li Hao, Kuninori Suzuki, Chika Kakuta, Junko Shimasaki, Yuji Sugita, Tatsuya Niwa, Yūko Fujioka, Takuo Osawa, Hitoshi Nakatogawa, Nobuo N. Noda

The paper shows Atg1 phosphorylates Atg2 to enable lipid transport for autophagosome formation in yeast.

bioRxiv · May 24, 2025 · PreprintCell Biology