Author

Congcong Chen

Shandong UniversityORCID 0000-0002-3606-5231Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

C E CheniD· 1 shared Dan He· 1 shared Hongze Niu· 1 shared Jing Qin· 1 shared Keyi ZhangiD· 1 shared Li Pan· 1 shared Mingxia Bi· 1 shared Pan Gao· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioengineering

C E ChenORCID

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2 papers

Recent·Most cited

Gram-scale one-pot enzymatic synthesis of CDP-ribitol by a designed bifunctional fusion enzyme

Xuyang Zhang, Li Pan, Yumeng Wang, Xianwei Liu, Mingxia Bi, Peixue Ling, Congcong Chen, Shuaishuai Wang

This paper describes a one-pot enzymatic method to produce CDP-ribitol at gram scale using a bifunctional fusion enzyme, achieving high yield and atom economy.

bioRxiv · Jul 29, 2026 · PreprintBiochemistry

An engineered IdeS variant with enhanced activity and performance for IgG degradation

Keyi Zhang, Wenhao Ma, Zhijie Wu, Zipei Ren, Congcong Chen, Yan Xia, Dan He, Z-F Yu, Hongze Niu, Jing Qin, Pan Gao, WY Yang, Yangguang Dai, Xiu Li, Zheyue Dong, , XC Wu

This paper engineers an improved IgG-degrading enzyme, IdeSM33, showing enhanced activity and IgG depletion in vivo, with therapeutic potential for autoimmune diseases and gene therapy.

bioRxiv · Jul 1, 2026 · PreprintBioengineering