Author

Z-F Yu

Shanghai Jiao Tong UniversityORCID 0000-0002-2224-8344Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

C E CheniD· 1 shared Congcong CheniD· 1 shared Dan He· 1 shared H Y Wang· 1 shared Hanjun LiiD· 1 shared Hongze Niu· 1 shared Jing Qin· 1 shared Junqi Cui· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioengineering

C E ChenORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintJul 1, 2026

An engineered IdeS variant with enhanced activity and performance for IgG degradation

Keyi Zhang, Wenhao Ma, Zhijie Wu…·XC Wu

This paper engineers an improved IgG-degrading enzyme, IdeSM33, showing enhanced activity and IgG depletion in vivo, with therapeutic potential for autoimmune diseases and gene therapy.

1 citation

experimental assaydrug response / drug discovery

𝕏 PostBluesky

Cell BiologybioRxivPreprintJun 6, 2026

Piezo1 transduces mechanical signals to inhibit osteoclast fusion and coordinate bone homeostasis

Ying Wang, H Y Wang, Tianyou Kan…·Z-F Yu

This study shows that Piezo1 transduces mechanical signals to inhibit osteoclast fusion and maintain bone homeostasis by activating a signaling pathway that suppresses osteoclast differentiation.

DOI 10.64898/2026.06.02.727841

mouseproteomics

𝕏 PostBluesky