Nicolás Toro

The paper identifies a UG5 reverse transcriptase-nitrilase antiviral module in Sinorhizobium meliloti that provides immunity against phages.

The paper analyzes retron diversity in the SPIRE metagenome, identifying novel type XI-like lineages and their ecological distribution.

The paper characterizes DRT10, a reverse transcriptase defense system, showing it is regulated by host exonuclease SbcB and a phage-encoded SSB-like protein.

This study identifies a post-translational toxin-antitoxin mechanism in Retron-Sen3 that activates phage defense independently of ssDNA synthesis and RecBCD surveillance.

This study identifies Retron-Eco11 as a bacterial defense system that uses helicase proteins to trigger effector toxicity against phage infection.

This study shows that type VI-B CRISPR-Cas systems with RT-Cas1 fusion proteins can acquire spacers from RNA, functioning independently of other systems.