Author

Claire Sie

University of British ColumbiaORCID 0000-0002-3629-6275Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Carolina TropiniiD· 3 shared Katharine M. NgiD· 3 shared Bohan DengiD· 2 shared Charlotte A ClaytoniD· 2 shared Deanna M. PepiniD· 2 shared Giselle McCallumiD· 2 shared Jerry HeiD· 2 shared Adam M. DeutschbaueriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersMicrobiology

Carolina TropiniORCID

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintOct 28, 2026

Engineering a gut bacterium depleted in industrialized microbiomes to survive malabsorption

Juan C. Burckhardt, Deanna M. Pepin, Jerry He…·Carolina Tropini

The paper engineers a gut bacterium to enhance osmotic resistance, enabling it to survive malabsorption in industrialized microbiomes.

DOI 10.64898/2026.10.27.762397

humanexperimental assay

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MicrobiologyCell Reports MedicinePeer-reviewedDec 22, 2025

In mouse and in vitro models, bowel preparation promotes pathogen colonization, translocation and exacerbation of inflammation

Charlotte A Clayton, Imogen Porter, Bohan Deng…·Carolina Tropini

This study shows that bowel preparation with PEG increases susceptibility to pathogens and exacerbates inflammation in mouse and in vitro models.

7 citations

mouseexperimental assay

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NeuroscienceBrain Behavior and ImmunityPeer-reviewedDec 12, 2024

Early-Life Gut Inflammation Drives Sex-Dependent Shifts in the Microbiome-Endocrine-Brain Axis

Olivia Sullivan, Claire Sie, Katharine M. Ng…·Annie Vogel Ciernia

This study investigates how early-life gut inflammation affects microbiome, endocrine, and behavioral outcomes, revealing sex-specific impacts on microbiota composition, hormone levels, and behavior.

19 citations

mousemetagenomics

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