Author
The Netherlands Cancer InstituteORCID 0000-0002-3660-504XUnclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Ana-Maria Cujba, Sergio Aguilar-Fernández, Adrien Antoinette…·Gary Reynolds
HARP integrates PBMC data from multiple studies to create a reference atlas with consensus annotations and identifies age, sex, and disease-related cellular modules.
Mayukha Bathini, Diana Bocaniciu, Fraser D. Johnson…·Rik G.H. Lindeboom
Andrea Rodgers Furones, Thijs Brands, Guusje Van Gameren…·Laia Querol Cano
This study shows that galectin-9 in dendritic cells is necessary for organizing HLA-II at immune synapses, which enhances CD4+ T cell activation and anti-tumor immunity.
Andrew G. T. Pyo, Adlina Chan, Joshua Rosenheim…·Benny Chain
The paper quantifies T cell response dynamics during primary SARS-CoV-2 infection, showing clone-intrinsic properties drive clonal kinetics and providing insights for vaccine design.
Felix Drost, Yang An, Irene Bonafonte-Pardàs…·Benjamin Schubert
The paper introduces mvTCR, a multimodal generative model for integrating TCR and transcriptome data to improve analysis of single-cell immune profiling data.
Hannah K. Neikes, Rik G.H. Lindeboom, Cathrin Gräwe…·Michiel Vermeulen
The paper quantifies how chromatin context affects transcription factor binding affinities genome-wide and shows DNA accessibility is the main determinant.