Andrew G. T. Pyo

This study shows that antibody-mediated antigen tethering helps balance affinity and diversity in germinal center B cells by improving robustness during affinity maturation.

This study shows that curved Vibrio cholerae cells swim more efficiently through mucus-like hydrogels than straight mutants, with curvature enhancing chemotaxis by reducing stalls.

This study develops a theoretical framework to show how membrane-anchored mobile tethers influence condensate wetting, localization, and migration by modifying surface tension and contact angle.

The paper develops a population dynamics model of B and TFH cells in germinal centers, showing reciprocal stimulation regulates their ratio and balances affinity maturation speed with B cell diversity.

The paper quantifies T cell response dynamics during primary SARS-CoV-2 infection, showing clone-intrinsic properties drive clonal kinetics and providing insights for vaccine design.