Frank Bellivier

This study identifies Gdf15 as a key mediator of lithium-induced collecting duct dysfunction and remodeling, linking spatial stress responses to functional and structural kidney injury.

The paper develops pathway-specific polygenic scores to predict lithium treatment response in bipolar disorder and finds associations with specific biological pathways.

This study investigates associations between mitochondrial metabolites and metabolic syndrome in bipolar disorder, finding significant links between lactate levels and metabolic syndrome markers, while cell-free mitochondrial DNA showed no association.

This study identifies genetic loci associated with suicide attempts and shows shared genetic architecture with psychiatric disorders and non-psychiatric risk factors.

This study investigates superficial white matter microstructure in schizophrenia and bipolar disorder using diffusion weighted imaging, finding altered fractional anisotropy in specific brain regions.

The paper shows that polygenic scores for depression traits predict lithium response in bipolar disorder patients, with lower genetic load linked to better treatment outcomes.

This paper conducts a GWAS on suicide attempt across psychiatric disorders, identifying genetic loci and showing polygenic risk for major depression predicts suicide attempt in multiple disorders.

This study identifies 114 genome-wide significant loci for schizophrenia and bipolar disorder, with specific subphenotype associations and four genes distinguishing the disorders.

This study finds that a higher genetic risk for schizophrenia is linked to poorer lithium response in bipolar disorder patients, suggesting potential for personalized treatment strategies.