Marion Leboyer

This study shows that fecal extracellular vesicles from ASD patients alter mouse behavior and gut motility by affecting the neuronal nitrergic pathway via microbial metabolites.

This study links elevated serum p-cresol levels to constipation in adults with high-functioning autism spectrum disorder and shows p-cresol induces constipation-like symptoms in mice.

The paper finds that CSMD2 is overexpressed in brain tissues of schizophrenia patients, while CSMD1 shows no difference, suggesting a dissociation between genetic risk and transcriptional output.

The paper introduces a multiscale resource integrating genetics, brain imaging, and clinical data from autistic individuals and their relatives to explore genetic and neurobiological patterns in autism.

This study investigates associations between mitochondrial metabolites and metabolic syndrome in bipolar disorder, finding significant links between lactate levels and metabolic syndrome markers, while cell-free mitochondrial DNA showed no association.

This study shows that elevated C4 expression in the mouse prefrontal cortex causes schizophrenia-like phenotypes including synaptic and cognitive deficits.

This study identifies a genome-wide significant variant for OC traits and shows shared genetic risk between OC traits and OCD.

This study investigates superficial white matter microstructure in schizophrenia and bipolar disorder using diffusion weighted imaging, finding altered fractional anisotropy in specific brain regions.

The paper shows that polygenic scores for depression traits predict lithium response in bipolar disorder patients, with lower genetic load linked to better treatment outcomes.

This paper conducts a GWAS on suicide attempt across psychiatric disorders, identifying genetic loci and showing polygenic risk for major depression predicts suicide attempt in multiple disorders.

This study identifies reproducible functional connectivity alterations in ASD using rs-fMRI across four large cohorts, linking them to clinical symptoms and brain regions.

This study finds that a higher genetic risk for schizophrenia is linked to poorer lithium response in bipolar disorder patients, suggesting potential for personalized treatment strategies.