Cristina Airoldi

Microbiome Modulation Uncouples Efficacy and Toxicity Induced by Programmed Death-1/Programmed Death-Ligand1 Blockade

This study shows that administering Prevotella melaninogenica to mice with multiple myeloma delays disease progression and enhances the efficacy of PD-1/PD-L1 blockade while reducing toxicity.

A modular model integrating metabolism, growth, and cell cycle predicts that fermentation is required to modulate cell size in yeast populations

The paper develops a multiscale computational model integrating metabolism, growth, and cell cycle in yeast to predict that fermentation modulates cell size under different growth conditions.