Anura Shodhan

Directional branch migration remodels the meiotic Holliday junction landscape

This study maps meiotic Holliday junctions genome-wide using HJSeq, showing directional branch migration during pachytene linked to transcription and the ZMM pathway.

Turning coldspots into hotspots: targeted recruitment of axis protein Hop1 stimulates meiotic recombination in Saccharomyces cerevisiae

This study shows that recruiting Hop1 to coldspots increases DSBs and recombination, demonstrating Hop1's sufficiency for DSB formation but not crossover pathway selection.

Noncanonical contributions of MutLγ to VDE-initiated crossovers during Saccharomyces cerevisiae meiosis

The paper shows that Mlh3 dependence of VDE-initiated crossovers varies with genomic location, and Pch2 influences this dependence across different loci.