Rohit Sharma

Precision survival estimation in acute myeloid leukemia using evolutionary learning-derived microRNA signature

This paper develops AMLS, an evolutionary learning method combined with SVR, to identify a miRNA signature for improved survival prediction in AML, achieving high prognostic accuracy.

Computational investigation of Scutellarein derivatives as an inhibitor against triple-negative breast cancer by Quantum calculation, and drug-designed approaches

The paper computationally designs Scutellarein derivatives as potential inhibitors for triple-negative breast cancer using quantum calculations and drug-design approaches, identifying DM03 and DM04 as promising candidates with strong binding affinity.

Anastrozole mediated modulation of mitochondrial activity by inhibition of mitochondrial permeability transition pore opening: An initial perspective

This study investigates anastrozole's effect on mitochondrial permeability transition pore (mPTP) by molecular docking, dynamics, and cell experiments, finding it more effective than cyclosporine A in inhibiting mPTP and improving mitochondrial function.

Enhanced specificity of high sensitivity somatic variant profiling in cell-free DNA via paired normal sequencing: design, validation, and clinical experience of the MSK-ACCESS liquid biopsy assay

The paper describes the development and clinical application of MSK-ACCESS, a liquid biopsy assay that improves the specificity of somatic variant detection in cell-free DNA by using paired normal sequencing.