Author

Cynthia Wu

University of California San DiegoORCID 0000-0002-3687-2199Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Cynthia Wu1 paper · Columbia University

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:eQTL / molecular QTL mapping· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Melissa GymrekiD· 3 shared Abraham A. PalmeriD· 2 shared Alon GoreniD· 2 shared An ZhengiD· 1 shared Andrey V. BzikadzeiD· 1 shared Daniel B. MunroiD· 1 shared David George AshbrookiD· 1 shared Eric M. MendenhalliD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenomics

Melissa GymrekORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Trex-QTL: A mixture-model for identification of genetic effects with global effects on molecular phenotypes

Cynthia Wu, Andrey V. Bzikadze, Tian Han Xu, Eric M. Mendenhall, Hao Chen, Francesca Telese, Oksana Polesskaya, Daniel B. Munro, Abraham A. Palmer, Alon Goren, Melissa Gymrek

Trex-QTL identifies trans-eQTLs with global effects on molecular phenotypes, showing improved power and replicating known loci in rat brain data.

bioRxiv · Aug 17, 2026 · PreprintGenomics

A novel quantitative trait locus implicates Msh3 in the propensity for genome-wide short tandem repeat expansions in mice

Mikhail O. Maksimov, Cynthia Wu, David George Ashbrook, Flavia Villani, Vincenza Colonna, Nima Mousavi, Nichole Ma, Lu Lu, Jonathan K. Pritchard, Alon Goren, Robert W. Williams, Abraham A. Palmer, Melissa Gymrek

The paper identifies a quantitative trait locus on chromosome 13 associated with STR expansion propensity in mice, implicating Msh3 in genome-wide mutation patterns.

Genome Research · May 1, 2023Peer-reviewedGenomics

Deep neural networks identify context-specific determinants of transcription factor binding affinity

An Zheng, Michael Lamkin, Cynthia Wu, Hao Su, Melissa Gymrek

The paper uses deep neural networks to identify context-specific determinants of transcription factor binding affinity and shows improved prediction performance over existing methods.

bioRxiv · Feb 26, 2020 · PreprintGenomics