M-Sec promotes the production of infectious HIV-1 virus through the exocyst complex
Reem M. Mahmoud, Masateru Hiyoshi, Randa A. Abdelnaser, Kazuaki Monde, Nami Monde, Takaaki Koma, Hidenobu Mizuno, Sara A. Habash, Naofumi Takahashi, Yosuke Maeda, Akira Ono, Shinya Suzu
This paper shows that M-Sec promotes HIV-1 production by facilitating Gag puncta formation and Env incorporation through PIP2, Ral, and the exocyst complex.
bioRxiv · Nov 13, 2025 · PreprintMicrobiology