Author

Yilin Lyu

Fudan UniversityORCID 0000-0002-3699-7776Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Hong LüiD· 2 shared Jungang ZhouiD· 2 shared Kunfeng Song· 2 shared Yao YuiD· 2 shared Haiyan ReniD· 1 shared Hao CheniD· 1 shared Pingping WuiD· 1 shared Tian TianiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersSynthetic Biology

Hong LüORCID

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2 papers

Recent·Most cited

Intergeneric chromosomal transfer in yeast results in improved phenotypes and widespread transcriptional responses

Yilin Lyu, Yi Shi, Kunfeng Song, Jungang Zhou, Hao Chen, Xueying Li, Yao Yu, Hong Lü

This study transfers chromosomes from Saccharomyces cerevisiae to Kluyveromyces marxianus, resulting in improved phenotypes and widespread transcriptional changes.

Nature Communications · Jan 8, 2026Peer-reviewedSynthetic Biology

Transfer of disulfide bond formation modules via yeast artificial chromosomes promotes the expression of heterologous proteins in Kluyveromyces marxianus

Pingping Wu, Wenjuan Mo, Tian Tian, Kunfeng Song, Yilin Lyu, Haiyan Ren, Jungang Zhou, Yao Yu, Hong Lü

This paper develops a yeast artificial chromosome system in K. marxianus to enhance heterologous protein expression by incorporating disulfide bond formation modules, achieving record-high glucoamylase yields.

mLife · Mar 1, 2024Peer-reviewedSynthetic Biology