Daniele Dell’Orco

This study investigates cortical responses in retinal degeneration using electrophysiological methods, finding preserved or enhanced cortical reactivity despite reduced visual input.

This study shows that retinal network dysfunction occurs before structural degeneration in severe GUCA1A cone-rod dystrophy, suggesting an early therapeutic window.

This paper investigates how the E111V mutation in GCAP1 affects dimerization and GC1 activity, showing that RD3 can partially restore cGMP production in mutated variants.

This study shows that delivering recombinant GCAP1 protein, either directly or via liposomes, modulates phototransduction in mouse retinas, with a mutation inducing a disease-like phenotype.