ImmunologyNature CommunicationsPeer-reviewed
Genome-wide screen of Mycobacterium tuberculosis-infected macrophages identified the GID/CTLH complex as a determinant of intracellular bacterial growth.
Nelson V. Simwela, Luana Johnston, Paulina Pavinski Bitar…·David G. Russell
The paper identifies the GID/CTLH complex as a host determinant suppressing antimicrobial responses against intracellular bacterial infections through a CRISPR screen in Mtb-infected macrophages.