Author
Xiaonan Liu
Chinese Academy of SciencesORCID 0000-0003-2708-0971Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2024-2026 · peak 1/yrCo-Author Collaboration Network
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- Molecular BiologybioRxivPreprint
Cytochrome P450 Enzyme Design by Constraining Catalytic Pocket in Diffusion model
Qian Wang, Xiaonan Liu, Hejian Zhang…·Huifeng Jiang
The paper designs artificial cytochrome P450 enzymes by applying a 'three-point fixation' model derived from structural and evolutionary analysis, resulting in enzymes with enhanced catalytic activity.