Author

Jie Gao

Chinese PLA General Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioengineering· 1 Immunology· 1 Microbiology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:rat· 1

Frequent Co-Authors

Bin Cai· 1 shared Christine M. LightiD· 1 shared Chun ZhouiD· 1 shared Guojun Wang· 1 shared Hong ZengiD· 1 shared Hua Chen· 1 shared Hui CheniD· 1 shared Jinliang WangiD· 1 shared

Activity by Year

2026-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperNeuroscience

Bin Cai

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Terminal Modification Reprograms Supramolecular Organization of Integrin Ligand Assemblies to Shape Cell Migration

Ziyi Su, Yanling Lin, Zhu Zhu, Xunwu Hu, Wenjing Hou, Qizheng Zhang, Yanbin Cai, Jie Gao, Zhimou Yang, Ye Zhang

This study shows that terminal modifications of integrin ligands can reprogram their supramolecular organization and function, affecting cell migration without altering the sequence.

bioRxiv · Sep 29, 2026 · PreprintBioengineering

PD-1 remodels SHP2 dynamics and drives the non-catalytic inhibition of T cell activation

Panyu Fei, Peng Jiao, Jie Gao, Hui Chen, Yu Zhang, Lu Chen, Peng Wu, Lina Chen, Salvatore Valvo, Michael Loran Dustin, Jizhong Lou, Chun Zhou, Wei Chen

This study reveals that PD-1 remodels SHP2 dynamics to inhibit T cell activation through a non-catalytic mechanism, independent of its phosphatase activity.

bioRxiv · May 22, 2026 · PreprintImmunology

Lesion-Level-Dependent Neuroendocrine Surge Precedes Neuroinflammation and Endoplasmic Reticulum Stress in the Hypothalamus After Spinal Cord Injury: Dual-Cohort Transcriptomic Evidence for a Temporally Ordered AVP Cascade

Lianhua Li, Hong Zeng, Ming Li, Jie Gao, Hua Chen, Bin Cai, Zhi Liu

This study identifies a temporally ordered hypothalamic cascade after spinal cord injury, showing an early AVP surge precedes neuroinflammation and ER stress, with transcriptomic evidence from two rat cohorts.

bioRxiv · Apr 22, 2026 · PreprintNeuroscience

Genome-wide CRISPR/Cas9 knockout screen identifies host factors essential for Bovine Parainfluenza Virus Type 3 replication

Jinyang Hao, Xiaoran Gao, Christine M. Light, Yuze Sun, Sha Lu, Yu Tian, Xia Gao, Yuan Su, Jie Gao, Xin Huang, Qianyi Zhang, Jinliang Wang, Rong Hai, Wei Hu, Guojun Wang

This study uses a genome-wide CRISPR/Cas9 knockout screen in bovine cells to identify host factors essential for BPIV3 replication, revealing SLC35A1 and LSM12 as critical for viral entry.

Science China Life Sciences · Jan 28, 2026Peer-reviewedMicrobiology